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Maternal hypothyroidism has been associated with increased risk for preeclampsia, miscarriage, stillbirth, preterm birth, and low-birth-weight infants (reviewed in 12)

Some research suggests these medications may influence this adaptive thermogenesis, though evidence remains preliminary and requires further investigation

Ozkan B et al (2023) Associations of N-terminal pro-B-type natriuretic peptide, estimated glomerular filtration rate, and mortality in US adults, (in eng)

As the gut is much more accessible than the brain and can be analyzed through stool samples, a bacterial biomarker is an attractive prospect

This occurs because gut bacteria are actively fermenting the prebiotic fiber, and the resulting gas production peaks before the microbiome stabilizes around its new bacterial balance