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10.1093/intimm/dxx031 Int Immunol

Slow release and K D = 0.90 pM was observed with nitrilotriacetic acid (NTA), whereas His showed fast release and substantially lower K D = 34.7 fM (50 mM HEPES, 50 mM NaCl, pH 7.4), which was explained with formation of ternary HisCuHSA complex

GHK-Cu has a variety of roles in the human body including, but not limited to promoting activation of wound healing, attracting immune cells, antioxidant and anti-inflammatory effects, and stimulating collagen and glycosaminoglycan synthesis to help reduce wrinkles and fine lines in skin

This makes them highly effective for managing chronic inflammation, tendonitis, rheumatoid arthritis, and sports injuries

Liu PK: DNA damage and repair in the brain after cerebral ischemia