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8 The recommended dosage of conventional isotretinoin is 0.5mg/kg/day given in two divided doses, with dose escalation to 1.0mg/kg/day as tolerated, for a duration of 15 to 20 weeks
non-oral contraceptive methods should be considered [1] Optimization strategy : Tirzepatide monotherapy should be optimized to the maximally tolerated dose with confirmed adherence before considering phentermine addition Cost considerations : Both medications can be expensive, particularly tirzepatide, which may limit accessibility Any decision to combine these medications should involve shared decision-making with written informed consent, thorough evaluation of the patient's medical history, current health status, weight loss goals, and potential contraindications
Cancer 5 , 7289 (2014)
[Revised in March 2016] [Accessed on 6th October 2022]
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