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There could be several causes behind this condition, like prolonged exposure to toxic chemicals, viral infections, inherited disorders, undergoing cancer treatment, and taking certain medicines

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More specifically, GLP-1R expression has been identified in several hypothalamic and basal forebrain regions, including the paraventricular nucleus, supraoptic nucleus, infundibular nucleus/arcuate nucleus, lateral hypothalamic area, and nuclei of the basal forebrain, where they exhibit relatively well-defined regional expression patterns (43, 44)

It is to build a complete metabolic picture

Curr Protoc Toxicol