Mol Metab
Notably, epidemiological data indicate that Asian populations develop diabetes at a significantly younger age than White populations, exhibiting elevated risks of disease-related complications and mortality, thereby imposing a considerable healthcare burden [117]
When combined, these drugs create overlapping cardiovascular stress: phentermine's stimulant effect paired with semaglutide's blood-pressure-modulating properties can lead to irregular heart rhythms, elevated blood pressure episodes, and increased risk of myocardial events
doi: 10.1186/s13073-016-0297-9 153 MaiuoloJ.GliozziM.MusolinoV.CarresiC.ScaranoF.NuceraS.et al
Sections were dewaxed and stained with a rabbit polyclonal anti-FITC (711900, Thermo Fisher Scientific, 1/100) plus secondary Alexa Fluor 488 antibody (Life Technologies, 1/200), and guinea pig anti-human insulin (A0564, Dako, 1/1000) plus secondary Alexa Fluor 546 antibody (Life Technologies, 1/1000) prior to confocal imaging as above