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The therapeutic efficacies of this IC were similar to those of interferon- treatment and the protocol for treatment was deemed to merit further optimization 83 Importantly, transient flares of alanine aminotransferase (ALT), reflecting injuries in liver function, were observed in a small percentages of IC-treated patients, but liver functions became normal during treatment or at the follow-up period

The monthly maintenance phase helps keep those improvements going long-term

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Herpes simplex virus type 2 UL34 protein requires UL31 protein for its relocation to the internal nuclear membrane in transfected cells