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However, the SUMMIT trial implemented stricter inclusion criteria (left ventricular ejection fraction (LVEF) 50%, age 40), resulting in closer alignment with the specific characteristics of the HFpEF population

Stop or at least limit alcohol consumption

En la posicin 3 sustituye el glutamato por arginina (Glu3Arg), lo que reduce drsticamente su afinidad por las protenas de unin (IGFBP), y aade una extensin N-terminal de 13 aminocidos que aumenta su estabilidad y semivida

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Protein sources: Chicken, fish, lean beef, Greek yogurt, eggs, cottage cheese, protein powder (whey or high-quality plant blend)