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Enhanced Energy and Vitality One of the most immediate and noticeable benefits is the dramatic increase in energy levels

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EXAMPLE 1 To assess the activity of the combination according to the invention for the treatment of erectile dysfunction, a randomised, double-blind placebo-controlled clinical trial was conducted

Yang et al., 2020) and epigenome (Louwies et al., 2019)

Figure 1 The biological effects of testosterone are mediated both by direct binding and activation of the androgen receptor, as well as indirectly through its metabolic conversion to biologically active derivatives, including 5-dihydrotestosterone (DHT) via 5-reductase and oestradiol via aromatization, which subsequently act through androgen and oestrogen receptors (ER/ER), respectively