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However, the specific regulatory modality used to control Notch may depend on evolutionary origins and tissue context

But that evidence is entirely animal-based

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Most users of any medication in this class experience peak symptoms during weeks 4 through 8 of dose escalation, with substantial improvement by week 12

"This could be an important step toward personalizing treatment for depression." Haroon and his team looked at 50 patients with depression not currently receiving antidepressant treatment