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Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%

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This protective response typically lessens as your body tolerates the medication and you follow proper dosing protocols that start low and increase gradually over 4 to 12 weeks

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doi: 10.21037/atm-21-4162

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Therefore, inulin and its metabolites modulate the balance of the immune response, setting a reasonable immune tension that allows T cells to clear harmful substances but avoids exaggerating the level of tissue damage

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The majority of patients do not require discontinuation of tretinoin therapy during RA-APL syndrome

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