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The existing methods for phenotypic selection of genetically modified mammalian cells are mainly based on three types of phenotypic markers: an exogenous drug resistance gene that permits screening for positive cells, a fluorescent protein, such as GFP, that allows isolating positive cells by FACS (fluorescence-activated cell sorting) (Wei et al., 2001
Melanotan 2 interacts with multiple receptors (MC1R, MC3R, and MC4R), hence its role in metabolic and sexual processes
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