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The active epitope should project outward from the nanoparticle corona, conjugation chemistry must minimize heterogeneity, and auxiliary ligands may be introduced to enhance tissue-specific tropism when required

Patients who continue exercising after reaching their target weight maintain their results more successfully than those who stop

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Additional concerns include potential kidney problems in patients with existing kidney disease and acute kidney injury in severe dehydration cases

the VEGFR2-blocking, human anti-VEGF antibodies of the present invention have important advantages in inhibiting the detrimental actions of tumor-associated macrophages