1034,1807,1808 An increase in thyroid C-cell hyperplasia, adenomas, and medullary thyroid carcinomas was observed in preclinical rodent studies of liraglutide, while exenatide has been shown to cause nodular C-cell lesions without medullary thyroid carcinoma, 1809,1810 leading to concerns regarding the potential for development of medullary thyroid carcinoma in persons with DM on GLP-1 RAs
Many patients present with normal HbA1c yet have chronically elevated insulin levels, indicating metabolic dysfunction
Other prescription weight loss medications on the market that act on the central nervous system to suppress appetite (though by a different mechanism than GLP-1 drugs) include bupropion-naltrexone (Contrave) and phentermine-topiramate (Qsymia)
[DOI] [PubMed] [Google Scholar] 351.Ji MS, Jeong MH, Ahn YK, et al
The team provides ongoing monitoring and support to ensure safety and effectiveness