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IGF-1 LR3 Quick Start IGF-1 LR3 is a synthetic, longer-acting analog of insulin-like growth factor 1 (IGF-1)

In the STEP clinical trial program evaluating Wegovy for weight management, participants achieved mean weight reductions of 12% to 15% of baseline body weight over 68 weeks, significantly exceeding results seen with lifestyle modification alone

Nausea appears to be common across all three medications

Additionally, proteins in this group exhibit binding affinities for small molecules (GO:0036094), carbohydrate derivatives (GO:0097367), and heterocyclic compounds (GO:1901363), underscoring their versatile roles in interacting with various biomolecules

Across several studies, these drugs seem to produce some biological effects that are partly independent of weight loss itself