UnitedHealthcare constantly monitors drugs that are under development as well as potential new uses for those already approved, explains Susan Maddux, chief pharmacy officer for UnitedHealthcare Employer & Individual
Specialized pharmacokinetic studies use radioactive isotope labeling or mass spectrometry to track drug levels in research settings, but these tests are not available in typical outpatient care
"The strange thing is that you can't find many GLP-1 receptors in all these other organs where GLP-1 seems to work," he added
Graham, PhD, MD, professor of radiology with the University of Iowa Health Care, who was not involved in the research, said, While weve not encountered such issues at University of Iowa Health Care, we are anticipating that we will eventually encounter abnormal FDG PET scans as the use of GLP-1 drugs becomes more common. Graham also described how increased FDG uptake might obscure abnormal findings and reduce the accuracy of FDG PET imaging, particularly in cases of cancer
The primary pathological hallmarks include the loss of dopaminergic neurons in the substantia nigra, the presence of Lewy bodies, neuroinflammation, oxidative stress, and mitochondrial dysfunction
.png?width=1280&auto=webp&quality=80&format=jpg&disable=upscale)
