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Once approved, treatment is fully managed in our clinic, where our medical staff guides proper administration, dosing, and ongoing monitoring

The activation of other pro-survival signaling pathways, such as the PI3K/Akt, MAPK, and NF-kB pathways, as well as the regulation of DNA repair mechanisms (e.g., ATM/ATR and Chk1/Chk2 pathways), also play critical roles in paclitaxel resistance

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It can also occur on areas that receive little sun exposure, such as the palms, soles of the feet, nails and genital skin, particularly in melanoma

Especially, there are several studies regarding glutathione peroxidase (GPX), a major enzyme in removing various reactive oxygen species