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The insulin spike from carbohydrates may slightly enhance creatine uptake into muscle cells, but more importantly, taking it with food reduces the chance of stomach upset

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[1737] Table 1

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For these experiments, glucose-free DMEM (Life Technologies, 21013-024) was supplemented with 2.5 mM glucose (Sigma), 10% FBS, and penicillin-streptomycin

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