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Gram-negative bacterial lipopolysaccharide (LPS) stimulates macrophages to produce IL-6 and IL-1, two cytokines that increase BBB permeability and are associated with seizure progression (136)

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The PAOX gene is located on chromosome 10q26.3 and is composed of 8 exons that generate three alternatively spliced mRNAs, each of which encode a distinct protein isoform

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