In a 2-year carcinogenicity study in Sprague Dawley rats, subcutaneous doses of 0.0025, 0.01, 0.025 and 0.1 mg/kg/day were administered (below quantification, 0.4-, 1-, and 6-fold the exposure at the MRHD)
Br J Cancer 73:940944 Donigan JM, Hyde MA, Goldgar DE, Hadley ML, Bowling M, Bowen GM (2018) Rate of recurrence of lentigo maligna treated with off-label neoadjuvant topical imiquimod, 5%, cream prior to conservatively staged excision
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Thorpe KM, Patel C, Harrison R, Eapen Z, Ambrosy A, Coker R, Jenkins W, Anderson M, Migdalis I, Eliasson B, Chiang C, Cuadrado J, Santos NG, Litvak M, Loureyro J, Maldonado N, Gaal LV, Mihaylova-Shumkova R, Akhras R, Grondin F, Gupta M, Jones M, Lonn E, Lastuvka J, Cadinot D, Chevts J, Grosskopf J, Heymer P, Jung T, Luedemann J, Maxeiner S, Milek K, Regner S, Rieker W, Seufert J, Dimitriadis G, Pagkalos E, Mucsi J, Bonadonna R, Cosmo SE, Ponzani P, Trevisan R, Jang HC, Lee EY, Yu J, Vidrio-Velzquez M, Viergever EP, Guttormsen G, Wium C, Gadzinski W, Krzyzagorska E, Madej A, Romanczuk P, Garganeeva A, Kharakhulakh M, Lesnov V, Vasilevskaya O, Dawood S, Calonge AN, Charneco MQ, Rodrguez IR, Lundman P, Sderberg S, Chen JF, Sansanayudh N, Zlova T, Cookson T, Akhter F, Baum H, Aguiar RBD, Cheung D, Cohen A, Farris N, Forgosh L, Hartman I, Hermany P, Kulback S, Labroo A, Little R, Mehta A, Moran J, Rasouli N, Tan M, Wynne A, Yazdani S, Stewart M, Patel P, Sabol MB, Casson E, Hereghty B, Fernandez-Salazar E, Donaldson J, Jarosz M, Richards J, McLaughlin P, Breneman J, Shitut A, Bhosale A, Naicker P, Dumbre S
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