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28 In the MONICA/KORA Augsburg surveys, the prevalence of peripheral neuropathy increased from 7.4% in individuals with normal glucose tolerance to 28.0% in those with T2DM as glucose tolerance worsened

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It can also affect nerves elsewhere causing problems such as urinary incontinence (leakage) and erectile dysfunction

Metformin tops this list, with well-documented effects on b12 levels