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Based on a 12-week, randomized, double-blind, placebo-controlled clinical trial in 410 healthy women experiencing digestive discomfort

( a ) Cells were treated with succinate (Succ) and olaparib (Olap) or cisplatin (Cis) alone or combined with or without KG supplementation (n = 4 technical replicates representative from 3 independent experiments)

Shearn CT, Saba LM, Roede JR, Orlicky DJ, Shearn AH, Petersen DR (2017) Differential carbonylation of proteins in end-stage human fatty and nonfatty NASH

TRPM2 is a non-selective cation channel with Ca 2+ permeability