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Nienaber A, Ozturk M, Dolman R, Blaauw R, Zandberg LL, van Rensburg S, Britz M, Hayford FEA, Brombacher F, Loots DT, et al

A further improvement was seen during the extension in those receiving NAC, although this failed to reach statistical significance compared with placebo, possibly due to the small numbers or due to the initial improvement being a placebo effect

Ageing: The glutathione product might decrease naturally with age

This suggests that these lipid-protein complexes enhance interactions with synaptic membranes, which affects the oligomerization and aggregation of -synuclein, and interferes with the catalytic activity of cytoplasmic lipid enzymes and lysosomal lipases, thereby affecting lipid metabolism