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Clinical trials specifically designed to assess nutrient synergy are also more expensive and require larger sample sizes compared to the trial designs employed in some studies discussed in this review

It is very important for the nurse to check current references for pediatric medication orders and to double-check safe dose ranges (SDRs) to prevent errors and injury

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however, this may be inadequate given the unpredictable effects of these medications on gastric emptying and the extremely long half-lives of the most commonly used GLP-1 agonist medications