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Obesity and overweight [internet]

Thus, in a nutshell, it is possible that the initial DNA damage that predisposes melanocytes to malignant transformation and cytogenetic alterations that later promote actual malignant transformation of the initially transformed melanocytes may be driven by dysregulation in melanin biosynthesis and by the increased cellular content of melanin [10]

"Management of patients with risk factors" Accessed on December 14, 2023 at Janumet

Compared with diet-induced obese models (23, 36, 37), Bbs5 / mice exhibited distinct metabolic and immune characteristics, including rapid weight gain, pronounced immune dysregulation, and accelerated deterioration of glucose homeostasis and pancreatic function

Virz GM, Mattiotti M, Clementi A, Milan Manani S, Battaglia GG, Ronco C, et al