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The authors hypothesize that this paradoxical worsening is due to a cytokine imbalance, similar to what is seen with the exacerbation of disease after administration of biological treatments like anti-TNF, which increases interferon (IFN)- release and leukocyte chemotaxis [25]

More common side effects from BCAA supplementation include: Headaches Pain Nausea Fatigue If you experience any side effects, you should stop taking BCAAs and talk to your doctor

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If your stomach is emptying more slowly, the timing of your medication absorption might shift, potentially leading to fluctuations in your hormone levels

First, side effects like nausea, vomiting, and diarrhea are fairly common, especially early on, and all of these can affect your bodys fluid balance (9)