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The authors also noted that further optimisation was needed, including work relating to high clearance in mice and off-target activity against monoamine oxidase A

For example, its possible to have an allergic reaction to an inert ingredient used in compounded semaglutide thats not used in a brand-name semaglutide

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However, others have voiced more serious concerns, acknowledging that bad breath might be a minor issue compared to other potential side effects of these powerful medications