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Most users notice weight loss within 48 weeks, with maximum results after 612 months of consistent therapy

In the STEP 1 trial published in the New England Journal of Medicine, patients receiving semaglutide 2.4 mg weekly plus lifestyle intervention lost an average of approximately 15% of their body weight over 68 weeks

Although early, these findings highlight how therapies developed for cardiometabolic disease may intersect with hallmarks such as telomere attrition

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Oxidative stress is greatly involved in the onset and exacerbation of colitis, and it is likely that an appropriate antioxidant will be an effective therapeutic agent for UC