Because GH and IGF-1 signaling can influence fluid balance, connective tissue, metabolism, and glucose regulation, potential GH-axis-related effects include: Water retention Peripheral edema Joint stiffness or discomfort Muscle aches Paresthesias or tingling Carpal-tunnel-like symptoms Changes in insulin sensitivity or glucose handling Adult GH replacement literature consistently identifies fluid-retention-related effects including edema, arthralgia, carpal tunnel syndrome, and paresthesias as common side effects of GH treatment
Pancreatitis has been a theoretical concern but has not been shown to increase meaningfully in large studies
And I'll tell you, I would say 99% of the people over the age of 30 have somewhat compromised glutathione levels
Middle-aged and older adults with poor sleep were more likely to have brains that looked older than their chronological age
For a time, all stocks of GLP-1 RAs had to be reserved for those already using these medications, which meant that thousands of people who could have benefitted from these medications were not able to access them