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In summary, semaglutide has proven to be a pinnacle of GLP-1 drug development so far: highly efficacious for glycemic control, capable of inducing substantial weight loss, and demonstrating broad benefits (cardiovascular, renal, and beyond)
Its weight-loss effects are primarily achieved through several mechanisms, including central appetite regulation via hypothalamic pathways enhancing satiety, delayed gastric emptying that prolongs postprandial fullness, improvement of insulin sensitivity and metabolic homeostasis, and reduction of visceral and hepatic fat depots, which may alleviate respiratory mechanical burden and metabolic stress in OSAS (34)
Benefit: Enhances collagen synthesis, evens skin tone, and fights dullness
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Protection against the effects of oxidative stress In addition to regulating cortisol levels, DSIP can support the body in the fight against oxidative stress
