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[3] Critical Illness Considerations Sermorelin is not recommended for patients with acute critical illnesses (e.g., postoperative complications or respiratory failure), as GH modulation may increase mortality risk in these populations

GLP-1 receptor agonists like semaglutide (Ozempic, Wegovy) and the dual GLP-1/GIP agonist tirzepatide (Mounjaro) have delivered significant advances in weight management and blood sugar control

But for those who are not yet on dialysis, there are a number of patients who probably could delay the need for dialysis if they take these medications, although that has yet to be proven

They stimulate insulin secretion from pancreatic beta cells in a glucose-dependent manner, meaning they promote insulin release only when blood glucose levels are elevated

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