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doi: 10.3389/fendo.2026.1765089 Received 10 December 2025 Revised 10 January 2026 Accepted 16 January 2026 Published 03 February 2026 Volume 17 - 2026 Edited by Bilal i, Ahi Evran University, Trkiye Reviewed by Krystyna Pierzchaa-Koziec, University of Agriculture in Krakow, Poland Nai-Kei Wong, Shantou University, China Updates Copyright 2026 Jiang, Liu and Chen

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79 , 80 Interest in the function of ascorbate in the lens was prompted by teleologic arguments, which suggested age-related compromises in ascorbate and compromises in lens function might be related

HRT addresses the root cause rather than managing each symptom with a separate medication