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6. Duca F et al

We conjecture that once established, such a proteopathy would no longer respond to B cell depletors (assuming these cells were the original source of the amyloidogenic seeds) after the cross-seeding event has taken hold

Some causes of B12 deficiency are: Pernicious Anemia Autoimmune Diseases Leaky Gut Syndrome Ulcerative Colitis, Crohns and Celiac Disease Small Intestinal Bacterial Overgrowth (SIBO) H Pylori Infection Prolonged Usage of Gastric Reflux meds Vegan and Vegetarian diets MTHFR gene mutations Bariatric Surgeries Excessive Alcohol Consumption B12 and the Methylation Cycle: Methylation is a critical process that happens trillions of times in every cell each minute

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Zhao, L., Huang, Y