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However, this study has notable clinical limitations: The second cohort (Cohort 2) only included 24 patients, confounding factors such as diet and concurrent medications were not adjusted for, and there is a lack of clinically standardized protocols for MDSC function detection

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10.1016/j.freeradbiomed.2014.07.019 46 PittsM.HoffmannP

Nevertheless, the potential implications of our results for ED prevention policies required validation in further clinical randomized controlled trials

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