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These drugs are contraindicated in patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2. Other potential risks include: Acute pancreatitis Gallbladder disease (cholelithiasis, cholecystitis) Acute kidney injury Hypersensitivity reactions Patients should be monitored for persistent abdominal pain, changes in renal function, and other signs that may require discontinuation or additional workup

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Ivanov II, et al

These changes indicate your GLP-1 receptors have adapted to your present dose

Use Official Reporting Channels : In addition to talking to your doctor, you can report side effects to regulatory agencies