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Assessing and supporting appropriately high levels of erythrocyte GSH is important for protecting cells and promoting overall health and longevity, and contributes significantly to safe and effective metal detoxification

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Other classes of agents (particularly metformin, but also incretins and SGLT2 inhibitors), do not cause hypoglycaemia in individuals who are normoglycaemic at baseline in the absence of other hypoglycemic agents

These benefits required dual GLP-1R/GLP-2R engagement, as PG-102 outperformed monospecific Fc fusion agonists or their combination and promoted coordinated receptor trafficking with delayed internalization