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While an empty stomach is still a great choice, the liposomal technology is designed to support high bioavailability regardless of when you take it

The standard treatment for vitamin B12 deficiency involves administering cobalamin (either hydroxo- or cyanocobalamin) via intramuscular injection

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Acknowledgments The authors are thankful for the financial support from the Henan Provincial Science and Technology Research Project (242102311184), Natural Science Foundation of Hubei province (2023AFD224), the Open Fund of Key Laboratory of Edible Oil Quality and Safety for State Market Regulation (SYYKF202310), and China Postdoctoral Science Foundation (2021M702937)