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Most of the studies have shown its therapeutic role in melasma, whereas some studies have contradicted this fact[] [Table 1]

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The broader preclinical record, reviewed exhaustively by Graf and Kastin [4, 5], includes sleep-architecture effects in rats and mice, and predominantly REM-related effects in cats a species-specificity that the delta sleep-inducing name does not capture

Separate acute from chronic, and put a boundary on duration If someone is intent on using it, the least risky scenario is short-term use around a clearly defined acute injury window, not ongoing use for months for chronic pain

doi: 10.1136/bjsports-2022-106568 164