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High-fat diet-induced ROS may promote proinflammatory signaling and stimulate nuclear factor-kappa B (NF-B) transcriptional factor, and hence inducing NF-B-dependent proinflammatory molecules, for instance, TNF-, interferon-, and iNOS [44]

In some embodiments, each long-chain fatty acid independently comprises 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, or 38 carbon atoms in the carbon chain

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