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Based on the findings, the researchers concluded that initiating GLP-1 therapy was associated with a modestly increased risk of fragility fractures in older adults with type 2 diabetes. They indicated the results may help physicians weigh potential skeletal risks against the drugs expected health benefits

If withdrawal symptoms arise, it may be necessary to pause the taper for a period of time or raise the dose of the opioid analgesic to the previous dose, and then proceed with a slower taper

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A lab coat is also highly recommended

Pain occurs in response to high or low temperatures