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Inclusion of vitamin C in the human diet explains why our non-synthesizing ancestors did not become extinct, as they found this an effective compensation for the mutations in the gulonolactone oxidase gene

This protective role is vital in tissues with high metabolic demands, such as the heart and brain, which are particularly susceptible to oxidative damage

GHK-CU is not FDA-approved for any medical indication

J Biol Chem 284:2245722466 Sontheimer H (2008) A role for glutamate in growth and invasion of primary brain tumors

Gene enrichment analysis revealed that the five genes were enriched primarily in oxidative and antioxidant signaling pathways (Fig