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Most participants who experienced GI side effects reported them during the dose escalation phase, with symptoms improving once a stable maintenance dose was reached

Part of each tissue was fixed in 4% paraformaldehyde for morphological examination, and the rest was frozen in liquid nitrogen and preserved at -80 for later experiments

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Our findings show that it is not enough to look only at genes, study co-author Elisheva Abberbock, also of Bar-Ilan University, said in a statement

Second, any food particles remaining in the mouth create a physical barrier between the medication and the mucosal surface