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Future approaches While possible biomarkers for PD in classical studies have been hypothesis-driven, attempts to develop effective procedures for the differential diagnosis of PD in its early stages have led to the performance of CSF multianalyte methods including systematic measurements of patterns of variation in proteins (proteomics) or small molecules (metabolomics)

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decrease, weakening GPP-1 and GIP act as complementary hormones of the incretin effect, complementing each other in the regulation of insulin secretion, glucose, appetite, and lipid metabolism

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