PubMed U.S
Spinal Cord Lesions: Symptoms include gait instability, sensory deficits, and motor weakness, often progressing to paraplegia in severe cases (Mair et al., 2023)
Retrieved November 12, 2017
As a potent antioxidant, glutathione neutralizes free radicals and protects the skin from oxidative stress, a primary culprit behind premature aging
Among them, HMOX1, SOD2, and NOS2 have become the key targets - which is consistent with their previous research that can protect renal tubules from oxidative damage, maintain mitochondrial antioxidant capacity, and regulate the oxidative-reductive imbalance associated with uremia ( The human renal tubular epithelial cell line HK-2 was selected as the in vitro model because it plays a crucial role in maintaining electrolyte and fluid balance, and is susceptible to the progression of CKD ( To deeply analyze the protective mechanism of AST against ischemic renal injury, we focused on two key and interrelated pathological processes in CKD: oxidative stress and cell senescence accompanied by DNA damage