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I've seen several success stories for one-time-only issues, but it's not guaranteed
While semaglutide has a wide safety margin and overdose deaths are extremely rare, exceeding your planned injection or oral dose may result in acute gastrointestinal distress and metabolic complications
[DOI] [PMC free article] [PubMed] [Google Scholar] 142.Wei Y, Long S, Zhao M, Zhao J, Zhang Y, He W, et al
Siavoshi F, Salmanian AH, Akbari F, Malekzadeh R, Massarrat S
However, clinicians should remain vigilant for signs of excessive metabolic suppression or thyroid dysfunction, particularly in patients with pre-existing thyroid conditions or those experiencing symptoms beyond cold intolerance, such as severe fatigue, hair loss, or cognitive changes that might suggest thyroid hormone imbalance requiring investigation
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