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Edited by: Aria IM, Jakobi WB, Poppser, Shchacter D, Shafritz D

The conversion of spermine to spermidine generates not only spermidine but also H 2 O 2 and 3-aminopropanal (3-AP)

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doi: 10.15252/embr.201540946 104 WangYJGolsonMLSchugJTraumDLiuCVivekKet al

When the membrane lipid was peroxided, the physical properties of lipid bilayers were altered: membrane fluidity was reduced, the ion gradient was destroyed, membrane permeability was elevated, and lateral diffusion was retarded (Kagan et al., 2017)