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With the transporters now available, glucose can enter the cell, blood glucose levels fall back toward normal, and the state of hyperglycemia is resolved (Navale & Paranjape, 2016)

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Patients who want a flexible treatment solution that matches their daily activities and comfort needs choose to microdose GLP-1 for their medical needs

General guidelines and dosing for patients with T2D: Initiate pramlintide at the 60 mcg dose taken immediately prior to major meals Titrate pramlintide to 120 mcg dose after 3 or more days with no clinically significant nausea Optimize insulin to achieve glycemic targets once the maintenance dose of pramlintide is reached and blood glucose concentrations are stable Practical Tips for Patients On Pramlintide Start With a Low Dose and Titrate Slowly Pramlintide can cause nausea, anorexia and vomiting, especially in T1D where a more gradual titration is required

(1992) Effect of diet treatment on enuresis in children with migraine or hyperkinetic behavior