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Weight gain affects men and women differently driven by different hormones, metabolic patterns, and life stages

Potential for Long-Term Weight Loss: Studies have shown that it can lead to clinically significant weight loss that can be sustained over time, even after the medication is discontinued

That is part of the story, but it is not the whole picture

Because they work through entirely different biological pathways, there is no mechanism conflict between the two therapies

In contrast, in older or underweight PD patients who are already vulnerable to malnutrition and frailty, appetite suppression and weight loss remain concerns [16, 17, 22]