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GLP-1, or glucagon-like peptide-1, spurs the pancreas to release insulin and slows the passage of food through the gut

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APXs are extremely sensitive to the concentration of AsA, which is reflected by the rapid decline in their activity at very low concentration (less than 20 M) of AsA (Shigeoka et al., 2002)

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The therapies were administered as single injections or infusions, and the regimens varied from study to study, ranging from a single dose to daily administration for a few days