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Silibinin targets FTH1, disrupts the NCOA4FTH1 interaction, reduces ferroptosis-mediated cell death, and alleviates renal dysfunction, pathological damage, and inflammation in ischemiareperfusion injury (IRI) AKI mice, effectively preventing ischemiareperfusion-induced renal injury (96)

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To enhance the biosafety of engineered live bacteria therapy, host toxicity tests are still needed, and the long-term retention of the bacteria in the body should be observed

10.1001/jama.2023.24945