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Animal model and surgical procedures Anagen induction assay with C57BL/6 mice For the anagen induction assay, 56 male C57BL/6 mice aged 7 weeks weighing between 20 g and 22 g were procured from Orient BIO (Seoul, Korea)

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Clonidine works through the brain and is often reserved for resistant hypertension or withdrawal-related symptoms, while propranolol acts on the heart and is commonly chosen when blood pressure control is needed alongside migraine prevention, anxiety symptoms, or heart conditions